Long Term Neuropsychological Follow-up in Patients With Herpes Simplex Encephalitis and Predominantly Left-sided Lesions.

Five patients with predominantly dominant cerebral hemisphere lesions due to herpes simplex encephalitis are described. Verbal amnesia was the main deficit but amnesic aphasia sometimes associated with impairment of remote memory also occurred. Semantic and episodic memory deficits were also explored in one case and the role of the right cerebral hemisphere in facilitating recovery of learning is discussed.

[Primarily unilateral herpes encephalitis. Long-term neuropsychological study of 9 cases].

Nine cases of post-herpetic encephalitis with predominant involvement of one temporal lobe at CT scan or MRI (6 on the left and 3 on the right sides) were studied 1 to 6 years after onset with repeated language and memory testing. The neuropsychological findings were well correlated with the lateralization and size of the lesions, as previously observed in unilateral temporal lobectomy. Compared with the usual bilateral form, the sequelae were mild, and all the patients, especially those with right hemisphere involvement, resumed a subnormal family life or social activity.

[Biological, psychometric and tomodensitometric study of treated neurosyphilis].

Results of follow-up examinations of the CSF in 6 patients with neurosyphilis, including 5 with general paresis, following treatment with high doses of aqueous penicillin G are reported. Persistence of any residual active infection of the nervous system could be eliminated since as well as fairly rapid restoration of normal CSF cytology and chemistry there was a slow reduction (and sometimes return to normal) of initially very high levels of immunoglobulins G, disappearance of their oligoclonal distribution (3 cases), and negativation of quantitative immunofluorescence serology (F.T.

[Left paramedian thalamic infarct. Memory and language study].

Unusual findings in a patient with a paramedian infarct of the left thalamus, shown by CT scan were the elective nature and long duration of memory disorders. Mild amnesia has been relatively stable for two years, and is apparent during tests as an anterograde verbal memory deficiency for all modalities (serial, associative, logical), without facilitation during learning or recall by semantic or phonologic cues. On the other hand, anterograde visual, gestual or tactile memory, and particularly retrograde verbal and visual memory are well retained.