Publications by authors named "N Fons Murillo"
Introduction: Crohn's disease (CD) varies by location, potentially affecting therapy efficacy and surgery risk, although research on this topic is conflicting. This study aims to investigate the independent association between CD location and therapeutic patterns.
Methods: We analyzed patients with CD diagnosed from January 2005 to May 2023 registered in the nationwide ENEIDA registry.
Article Synopsis
- Over the last decade, research has focused on how mechanical power contributes to ventilation-induced lung injury and its potential link to ICU mortality, but most studies have only looked at early mechanical ventilation data.
- This study analyzed mechanical power in patients ventilated for over 24 hours in a Spanish ICU, determining how prolonged exposure to high mechanical power impacts mortality rates and hospital stay duration.
- Researchers established that a mechanical power threshold of 18 J/min significantly correlates with increased ICU mortality; specifically, the risk of death rises by 0.1% for each additional hour patients are ventilated above this threshold.
Background: In standard weaning from mechanical ventilation, a successful spontaneous breathing test (SBT) consisting of 30 min 8 cmHO pressure-support ventilation (PSV8) without positive end-expiratory pressure (PEEP) is followed by extubation with continuous suctioning; however, these practices might promote derecruitment. Evidence supports the feasibility and safety of extubation without suctioning. Ultrasound can assess lung aeration and respiratory muscles.
View Article and Find Full Text PDFBackground: Telerehabilitation in spinal cord injury (teleSCI) is a growing field that can improve access to care and health outcomes in patients with spinal cord injury (SCI). The clinical effectiveness of teleSCI is not known.
Objectives: To compare independence in activities of daily living and mobility capacity in patients following teleSCI and matched controls undergoing traditional rehabilitation.
Natural products obtained from (Anamu-SC) and (P2Et) have been used for cancer treatment, but the mechanisms by which they exert their antitumor activity appear to be different. In the present work, we show that the Anamu-SC extract reduces tumor growth in the 4T1 murine mammary carcinoma model but not in the B16-F10 melanoma model, unlike the standardized P2Et extract. Both extracts decreased the levels of interleukin-10 (IL-10) in the B16-F10 model, but only P2Et increased the levels of tumor necrosis factor alpha (TNFα) and interferon gamma (IFNγ).
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