A prospective observational cohort study of HIV infection in Indonesia: baseline characteristics and one-year mortality.

Introduction: The incidence rate of newly diagnosed HIV infection in Indonesia decreased from 21 per 100,000 in 2011 to 10 per 100,000 in 2021. Despite this progress, AIDS-related deaths among people living with HIV (PLWH) increased from 3.4% in 2010 to 4.

Does Meaning in Life Mediate Associations Between Suffering and Subsequent Mental Well-Being? Longitudinal Evidence From Two Non-Western Samples.

Narrative accounts have documented the potential for suffering to degrade a person's well-being by undermining their sense of meaning in life, but few studies have investigated this among nonclinical samples living in non-Western contexts of the Global South. Leveraging data from a set of three-wave longitudinal studies with younger Indonesian (Study 1: Wave 1 [December 2020], Wave 2 [January 2021], Wave 3 [February 2021]; N = 620) and Colombian adults (Study 2: Wave 1 [August/September 2021], Wave 2 [October/November 2021], Wave 3 [February 2022]; N = 2626), the present research used causal mediation methods within a counterfactual framework to examine whether the associations between suffering (Wave 1) and subsequent anxiety symptoms, depression symptoms, and general mental health (Wave 3) are mediated by meaning in life (Wave 2). Mediation analyses in both studies provided some evidence indicating that overall suffering (Wave 1) is indirectly associated with worse subsequent mental well-being on all three outcomes (Wave 3) via lower meaning in life (Wave 2).

Development of inulin nanocarrier for effective oral delivery of insulin: synthesize, optimization, characterization, and biophysical study.

The susceptibility of insulin against gastric acid degradation presents a major challenge for oral insulin delivery. The potential of biopolymer-based nanocarriers was investigated in order to address this issue. Inulin, a biopolymer produced by the halophilic bacterium Salinivibrio sp.

Pharmacology, phytochemistry and toxicity of a review.

belongs to the Ophioglosaceae family is referred to as in China. Historically, this terrestrial plant has been utilised for its anti-inflammatory properties and treatment of various ailments, with several scientific studies corroborating its efficacy. Compounds involved in it pharmacoloogy activities are Ugonin (U,J,K,M) and Neougonin A.

Autoimmune rheumatic transitional care model development.

Aim: To develop a transitional care model for autoimmune rheumatic disease patients based on the needs analysis.

Method: Mixed Method, Explanatory sequential design (QUAN-qual) has been conducted. Quantitative data were collected through medical record and structured interviews.