Publications by authors named "N Fırat"
Osteonecrosis of the femoral head can lead to end-stage osteoarthritis when left untreated. The incidence has been on the rise since the onset of the COVID-19 pandemic. Core decompression of the femoral head is usually the first line of surgical treatment when conservative options fail.
View Article and Find Full Text PDFThe importance of leucine-rich α-2 glycoprotein-1 in acute calculus cholecystitis.
Eur Rev Med Pharmacol Sci
May 2024
Objective: The aim of this prospective, single-center cohort study was to analyze serum leucine-rich α-2-glycoprotein-1 (LRG1) expression in patients with acute cholecystitis (AC) and to investigate its variation depending on symptom duration.
Patients And Methods: Participants were divided into patients with AC and a healthy control group. At the time of diagnosis, blood samples were collected, and symptom onset times were questioned.
Article Synopsis
- This study compares two surgical methods, Hartmann's procedure (HP) and resection with primary anastomosis (RPA), for treating acute left-sided colonic emergencies among 1215 patients from 204 centers globally.
- Results showed that while HP was the more common treatment (57.3%), RPA was favored for younger patients with fewer health issues and those needing surgery sooner.
- The study concluded that although HP is still widely used, RPA might be the better option, emphasizing the importance of patient characteristics and surgeon experience in determining treatment choice.
Article Synopsis
- Hypertension is a major cause of mortality with unknown origins, and this study explores the relationship between nesfatin-1, adropin, claudin-2, and renalase levels with blood pressure and kidney health.
- Adult male Sprague Dawley rats were divided into control and hypertension groups to assess the effects of angiotensin II on blood pressure and kidney function over a week.
- Findings indicated that renalase levels increased while claudin-2 levels decreased in hypertensive rats, suggesting both proteins may contribute to kidney dysfunction related to hypertension, necessitating further research.
Objective: Surgical site infections (SSI) are incomparably troublesome and complicated, and some of them require an open abdomen (OA) procedure. While deciding the timing of abdominal closure, wound area calculation method and laboratory parameters can be used to guide the timing of abdominal closure after OA procedures.
Patients And Methods: The records of the patients who had undergone open abdomen during their treatment course and were followed up with vacuum-assisted closure (VAC) technique between December 2015 and December 2019 were retrospectively analyzed.