Publications by authors named "N Esfandiari"

Supercritical fluid-based methods have been receiving increasing popularity in the production of pharmaceutical nanoparticles due to their ability to control the size and distribution of the particles and offer high purity products. The gas anti-solvent method is one of the methods in which a supercritical fluid serves as an anti-solvent. The aim of this work is to develop pazopanib hydrochloride nanoparticles as an anti-cancer agent by the supercritical GAS method.

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Afirma Genomic Sequencing Classifier (GSC) testing has been utilized for further risk stratification of thyroid nodules categorized as atypia of undetermined significance (AUS). The 2023 Bethesda system subcategorizes AUS diagnosis into AUS with nuclear atypia (AUS-N) and other atypia (AUS-O). The current study aims to determine if performance of GSC testing differs between the two AUS subcategories and between single AUS cohort and repeat AUS cohort.

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Article Synopsis
  • Natural biopolymers like bacterial cellulose and chitosan are valuable in healthcare for applications like tissue engineering and drug delivery due to their favorable properties (biodegradable, biocompatible, etc.).
  • A new magnetic nanocomposite made from these materials (along with iron oxide) was developed for use as a scaffold in tissue engineering, enhancing its applications such as drug delivery and cancer treatment.
  • The study found that the magnetic nanocomposite exhibited excellent mechanical properties, low toxicity, and a high degree of biodegradability, making it a promising material for future healthcare applications.
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Article Synopsis
  • The study aimed to evaluate how secondary health conditions impact the quality of life and wellbeing of Canadians with spinal cord injury using four different measurement tools.
  • The analysis included data from 364 adults living with spinal cord injuries, highlighting a trend where higher problem ratings from secondary health conditions related to lower quality of life scores.
  • Significant differences were found in the outcomes across the various instruments used, with certain conditions like respiratory issues and depression being linked to the lowest wellbeing ratings.
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Background/objective: Follicular thyroid cancer without an intrathyroidal primary cancer is rare. We present a patient with multifocal pulmonary metastatic follicular thyroid cancer without apparent cancer within her thyroid.

Case Report: A 44-year-old woman was referred to the thyroid cancer clinic via telemedicine for evaluation of intrapulmonary thyroid tissue.

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