Delayed neuromuscular fatigue recovery unveils reduced fatigue tolerance in elderly following maximal intermittent exercise.

The aim of the study was to assess the impact of aging on neuromuscular fatigue and recovery. Ten young (23.08 ± 1.

Blunted cerebral hemodynamic responses to incremental exercise in patients with end-stage renal disease.

Purpose: The aims of this study were to compare cerebral hemodynamics and maximal oxygen uptake (VO) in patients with end-stage renal disease (ESRD) vs. age-matched healthy controls during maximal exercise.

Methods: Twelve patients with ESRD and twelve healthy adults (CTR group) performed exhaustive incremental exercise test.

Hemodynamic and neuromuscular basis of reduced exercise capacity in patients with end-stage renal disease.

Purpose: The present study aimed to characterize the exercise-induced neuromuscular fatigue and its possible links with cerebral and muscular oxygen supply and utilization to provide mechanistic insights into the reduced exercise capacity characterizing patients with end-stage renal disease (ESRD).

Methods: Thirteen patients with ESRD and thirteen healthy males (CTR group) performed a constant-force sustained isometric contraction at 50% of their maximal voluntary isometric contraction (MVC) until exhaustion. Quadriceps muscle activation during exercise was estimated from vastus lateralis, vastus medialis, and rectus femoris EMG.

Muscle oxygen supply impairment during maximal exercise in patients undergoing dialysis therapy.

This study aimed to investigate whether Chronic Kidney Disease (CKD) influences O supply including O delivery and release to the active muscles during maximal physical exercise. Twelve CKD patients undergoing dialysis therapy (HD group) and twelve healthy adults (CTR group) performed an incremental exercise test to determine maximal oxygen uptake (VO). Throughout the exercise, near-infrared spectroscopy allowed the investigation of changes in oxyhemoglobin (∆OHb), deoxyhemoglobin (∆HHb), and total hemoglobin (∆THb) in the vastus lateralis muscle.

Peripheral fatigue regulation during knee extensor exercise in type 1 diabetes and consequences on the force-duration relationship.

Purpose: This study aimed to examine if peripheral fatigue is adjusted during knee extensor (KE) exercise in order not to surpass a critical threshold patient with type 1 diabetes (T1D) and the consequences of this mechanism on the force-duration relationship.

Methods: Eleven T1D individuals randomly performed two different sessions in which they performed 60 maximum voluntary contractions (MVC; 3 s contraction, 2 s relaxation). One trial was performed in the non-fatigued state (CTRL) and another after fatiguing neuromuscular stimulation of the KE (FNMES).