Publications by authors named "N E Mayo"

Purpose: Brain health is a dynamic state involving cognitive, emotional, and motor domains. Measuring brain health is a challenge owing to the uncertainty as to whether it is one or many constructs. This study aimed to contribute evidence for brain health as a unified construct by estimating the strength of relationships between and among patient-reported items related to the brain health construct in a population with brain vulnerability owing to HIV.

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Objective: To estimate the extent to which comorbidity, polypharmacy, and anticholinergic/sedative burden interrelate to influence cognitive ability, perceived cognitive deficits and physical frailty in people living with HIV.

Design: Cross-sectional Structural Equation Modeling (SEM) of data from 824 older people living with HIV in Canada, participating in the Positive Brain Health Now study.

Method: SEM was used to link observed variables, including comorbidity, polypharmacy, anticholinergic and sedative burden, to cognitive ability and two latent constructs - physical frailty and perceived cognitive deficits (PCD).

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Article Synopsis
  • The study examined the short-term effects of an educational workshop paired with either an outdoor walking group or weekly reminders on older adults' outdoor walking and overall well-being.
  • It involved a randomized controlled trial with 190 community-dwelling seniors, dividing them between a 10-week outdoor walk group and those receiving weekly reminders after an educational session.
  • Results showed no significant difference in outdoor walking minutes between groups at various time points, although the outdoor walking group exhibited improvements in walking capacity after the initial phase.
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Article Synopsis
  • Researchers at McGill University created a small device called Heel2Toe™ that makes a sound to help people with Parkinson's improve their walking.
  • In a study with 27 participants, those using the Heel2Toe™ sensor showed better walking results compared to those using a workbook.
  • Most people using Heel2Toe™ reported being happy with the device, suggesting it could be a helpful tool for improving gait in Parkinson's patients.
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