Coronavirus disease 2019 (COVID-19) is caused by the novel SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) first discovered in Wuhan, Hubei province, China in December 2019. SARS-CoV-2 has infected several millions of people, resulting in a huge socioeconomic cost and over 2.5 million deaths worldwide.
View Article and Find Full Text PDFEvidence indicates a critical role of neuroinflammatory response as an underlying pathophysiological process in several central nervous system disorders, including neurodegenerative diseases. However, the molecular mechanisms that trigger neuroinflammatory processes are not fully known. The discovery of bitter taste receptors in regions other than the oral cavity substantially increased research interests on their functional roles in extra-oral tissues.
View Article and Find Full Text PDFElectronic circuits and systems employed in mission- and safety-critical applications such as space, aerospace, nuclear plants etc. tend to suffer from multiple faults due to radiation and other harsh external phenomena. To overcome single or multiple faults from affecting electronic circuits and systems, progressive module redundancy (PMR) has been suggested as a potential solution that recommends the use of different levels of redundancy for the vulnerable portions of a circuit or system depending upon their criticality.
View Article and Find Full Text PDFStress is a nonspecific response to a threat or noxious stimuli with resultant damaging consequences. Stress is believed to be an underlying process that can trigger central nervous system disorders such as depression, anxiety, and post-traumatic stress disorder. Though the pathophysiological basis is not completely understood, data have consistently shown a pivotal role of inflammatory mediators and hypothalamo-pituitary-adrenal (HPA) axis activation in stress induced disorders.
View Article and Find Full Text PDFMultiplication is a widely used arithmetic operation that is frequently encountered in micro-processing and digital signal processing. Multiplication is implemented using a multiplier, and recently, QDI asynchronous array multipliers were presented in the literature utilizing delay-insensitive double-rail data encoding and four-phase return-to-zero (RTZ) handshaking and four-phase return-to-one (RTO) handshaking. In this context, this article makes two contributions: (i) the design of a new asynchronous partial product generator, and (ii) the design of a new asynchronous half adder.
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