[The impact of anemia on content and physical chemical characteristics of membranes of erythrocytes in pregnant women].

The article deals with the study of deformability of erythrocytes, lipid protein content and physical chemical characteristics was cytoplasmic membrane of erythrocytes in women aged 21-26 years with pregnancy taking normal course and complicated with anemia. In women with pregnancy complicated with anemia, by the period of 32-34 weeks in membranes of erythrocytes the percentage of lysophosphatids and cholesterol is decreased while the number of whole phospholipids and phosphatidyl inositols is decreased. The variance analysis demonstrated that the percentage of impact of anemia on the content of whole phospholipids consisted 11.

[Free-radical oxidation in liver during experimental widespread purulent peritonitis].

One of the most powerful damaging factors during inflammation is hyperactivation of the free-radical oxidation processes. The condition of lipid peroxidation (LPO) and antioxidant activity (AOA) systems in liver has been studied in experiment on 55 male Chinchilla rabbits with widespread purulent peritonitis (WPP) model. The development of WPP leads to expressed of free-radical oxidation processes in liver that is manifested by systemic accumulation of toxic LPO products and a decrease in the activity of antioxidants.

[Correction of protein-lipid composition in liver mitochondria during experimental widespread purulent peritonitis].

Experiments performed in a group of 55 chinchilla rabbits showed that the development of widespread purulent peritonitis is accompanied by the expressed changes of protein-lipid structure of liver mitochondria. A comparative analysis of the application of metabolic preparations citoflavin and neoton for the purpose of eliminating pathological deviations in the structure of liver mitochondrian has been carried out. The application of citoflavin more effectively prevents decrease in total phospholipids and cholesterol in mitochondrial membranes.

[The correction of the mitochondrial lipid spectre in liver by the experimental peritoniti].

The experiment has been carried out on 55 male rabbits of chinchilla breed. For the first time in comparative aspect influence of preparations "Citoflavin" and "Neoton" on a phospholipid spectrum of liver mitochondrial membranes is studied at an experimental widespread purulent peritonitis. It is established that in the postoperative period "Citoflavin", which contains amber acid, influences on phospholipid structure of mitochondria of animals with a widespread purulent peritonitis by percentage decrease of lisophosphatides, level increase of polyglycerophosphatide and cardiolipin more effectively.

[Effect of reamberin on the lipid spectrum of the liver mitochondria in experimental widespread purulent peritonitis].

Lipid spectrum of liver mitochondria has been studied in a group of 46 Chinchilla rabbits with experimental widespread purulent peritonitis. It is established that the drug reamberin that contains succinic acid produces a positive effect on the protein spectrum of liver mitochondria under these conditions, which is manifested by a decrease in the content of lysophosphatidylcholine and increases the levels of polyglycerophosphatides and sphyngomyelin.