Publications by authors named "N E Hynes"
Exploratory analysis of Type B Aortic Dissection (TBAD) segmentation in 2D CTA images using various kernels.
Comput Med Imaging Graph
December 2024
Article Synopsis
- - Type-B Aortic Dissection is a serious cardiovascular issue that impacts 3.5 people per 100,000 each year and involves a tear in the aorta's inner layer; this study focuses on using 2D Convolutional Neural Networks (CNN) for segmenting relevant areas in CT angiography images.
- - Researchers tested three variations of the U-Net model, with the U-Net using the VGG19 encoder achieving the highest performance scores: 80.48% mean Dice score and 72.93% IoU score.
- - The results showed that while the 2D U-Net models performed well in segmenting true and false lumen, they were less effective in false lumen thrombus segmentation compared
On the Importance of Including Cohesive Zone Models in Modelling Mixed-Mode Aneurysm Rupture.
Cardiovasc Eng Technol
October 2024
Introduction: The precise mechanism of rupture in abdominal aortic aneurysms (AAAs) has not yet been uncovered. The phenomenological failure criterion of the coefficient of proportionality between von Mises stress and tissue strength does not account for any mechanistic foundation of tissue fracture. Experimental studies have shown that arterial failure is a stepwise process of fibrous delamination (mode II) and kinking (mode I) between layers.
View Article and Find Full Text PDFOver the past two decades, there has been extensive research into surveillance methods for the post-endovascular repair of abdominal aortic aneurysms, highlighting the importance of these technologies in supplementing or even replacing conventional image-screening modalities. This review aims to provide an overview of the current status of alternative surveillance solutions for endovascular aneurysm repair, while also identifying potential aneurysm features that could be used to develop novel monitoring technologies. It offers a comprehensive review of these recent clinical advances, comparing new and standard clinical practices.
View Article and Find Full Text PDFBackground: Tyrosine kinase inhibitors targeting the vascular endothelial growth factor (VEGF) inhibitor pathway with immune checkpoint blockade have shown promising outcomes in managing metastatic renal cancer. However, they increase the risk of a person developing high blood pressure and cardiovascular complications.
Case Summary: In this study, we report the case of a 73-year-old woman on axitinib and pembrolizumab for her Stage 4 renal cell carcinoma.