We estimated the strength of immune response to chlamydial infection in patients with CHD. It was most pronounced in CHD patients with atrial fibrillation (AF). There was close relationship between past chlamydial infection and markers of inflammation (CRP and TNF-alpha).
View Article and Find Full Text PDFThis work was designed to study characteristics of cardiac fibrosis and inflammation associated with idiopathic atrial fibrillation (AF) and AF with concomitant arterial hypertension (AH). The same parameters were investigated in connection with different types of arrhythmia. It is shown that patients with AF have increased levels of serum markers of fibrosis and inflammation (C-terminalpropeptide of type I procollagen (PICP) and IL-6); they are especially high in case of combination ofAF and AH.
View Article and Find Full Text PDFVestn Ross Akad Med Nauk
April 2014
Aim: To study the parameters of the structural and functional state of the myocardium in patients with hypertension, to determine their prognostic value on the risk of atrial fibrillation (AF).
Patients And Methods: The study involved 72 people: patients with hypertension and AF, with isolated hypertension and apparently healthy individuals. All of them performed echocardiography, blood pressure monitoring and monitoring of cardiogram.
Arrhythmogenic role of proinflammatory cytokines is still unclear despite of wide discussion on inflammatory arrhythmogenic mechanisms. The main goal of study was to compare levels of tumor necrosis factor a, interleukin 6 and interleukin 4 in hypertensive patients with and without ventricular rhythm disturbances. The study included 100 cases, 50 of those had ventricular arrhythmias.
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