The Effect of Uphill and Downhill Slopes on Weight Transfer, Alignment, and Shot Outcome in Golf.

The aim of the study was to examine changes in weight transfer, alignment, and shot outcome during golf shots from flat, uphill, and downhill slopes. Twelve elite male golfers hit 30 shots with a 6-iron from a computer-assisted rehabilitation environment used to create 5° slopes while collecting 3-dimensional kinematics and kinetics of the swing. A launch monitor measured performance outcomes.

Outcome in children with Down's syndrome and acute lymphoblastic leukemia: role of IKZF1 deletions and CRLF2 aberrations.

Children with Down's syndrome (DS) have an increased risk of developing acute lymphoblastic leukemia (ALL) and have a low frequency of established genetic aberrations. We aimed to determine which genetic abnormalities are involved in DS ALL. We studied the frequency and prognostic value of deletions in B-cell development genes and aberrations of janus kinase 2 (JAK2) and cytokine receptor-like factor 2 (CRLF2) using array-comparative genomic hybridization, and multiplex ligation-dependent probe amplification in a population-based cohort of 34 Dutch Childhood Oncology Group DS ALL samples.

The preparation of crystalline human L-lactate--nicotinamide--adenine dinucleotide oxidoreductase isoenzyme 1 involvoing preparative polyacrylamide-gel electrophoresis.

A method is presented for the preparation of human heart lactate dehydrogenase (l-lactate-NAD(+) oxidoreductase; EC 1.1.1.