Publications by authors named "N E Fiehn"

Article Synopsis
  • The study aimed to assess the effectiveness of machine learning models in predicting clinically-defined Stage III/IV periodontitis using self-report questionnaires and demographic data.
  • Researchers extracted relevant data from two Danish population studies to develop and validate cross-validated machine learning models, testing them with large sample sizes from both cohorts.
  • Results showed that while the models demonstrated some predictive capabilities, with moderate accuracy levels, they still had limitations in sensitivity and specificity for predicting Stage III/IV periodontitis.
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Aim: To investigate the association between previous periodontal treatment and recurrent events after first-time myocardial infarction (MI).

Materials And Methods: From the Danish nationwide registries, patients with first-time MI between 2000 and 2015 were divided into three groups according to oral health care within 1 year prior to first-time MI. A multiple logistic regression model provided adjusted odds ratios (ORs) with 95% confidence intervals (CIs) to assess the 3-year risk of major adverse cardiovascular events (MACE).

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Objectives: Identifying additional information obtained by X-rays combined with clinical examination concerning primary caries, caries adjacent to restorations and quality of restorations.

Material And Methods: A total of 240 adult patients, equally distributed in gender and six age-groups, were randomly selected from an original study population of 4,402 subjects (DANHES). Clinical and radiographical registrations on occlusal and approximal surfaces in posterior teeth were categorized into unrestored surfaces (sound/primary caries) and restored surfaces (without/with caries adjacent to restorations).

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The AB0 blood group has been linked to ischaemic heart disease, stroke, and periodontal disease, while the Lewis blood group has been linked to ischaemic heart disease and obesity, all of which have been associated with periodontitis. AB0 or Lewis blood group phenotype may therefore constitute common hereditary components predisposing to these disorders. In this study, we investigated if blood group phenotype associated with periodontitis in a subpopulation consisting of 702 participants from a Danish cross-sectional cohort and, secondarily, attempted to confirm their association with hypertension, ischaemic heart disease, stroke, and obesity.

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The aim was to elucidate whether levels of circulating antibodies to and correlate to loss of attachment, as a marker for periodontitis and cardiovascular disease (CVD). Sera were collected from 576 participants of the Danish Health Examination Survey (DANHES). Immunoglobulin G antibodies against lipopolysaccharide (LPS) and protein antigens from the a, b and c serotypes of and were quantified by titration in ELISA plates coated with a mixture of antigens prepared by disintegration of bacteria.

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