[TREATMENT OF ERECTILE DYSFUNCTION FOLLOWING TRANSVESICAL PROSTATECTOMY].

This study examines the efficacy and safety of phosphodiesterase type 5 (PDE-5) inhibitors in treating erectile dysfunction after transvesical prostatectomy. The study involved 63 men aged 55 to 68 years, divided into two groups--29 and 34 patients, respectively. Patients in group 1 received 50 mg of sildenafil citrate (Ereksezil®) on a daily basis, in group 2--100 mg of sildenafil citrate (Ereksezil®) on demand.

[Dependence of skeletal muscle fatigue on the membrane polarization of the different types of muscle fibers in tourniquet shock].

Fatigue, polarization level and excitability of striated muscle fibers from ischemia zone were studied on experimental rats under the tourniquet shock. It was established that violation-mediated contraction and fatigue of skeletal muscle was associated with a decrease in a number of muscle fibers with high level of MPP. The article discussed the mechanisms of fatigue and depolarization of muscle fibres in tourniquet shock.

[Mechanism of the contractile function of masseter muscles in experimental rat botulism].

Injection of the sublethal dose of botulinic toxin into one of the masseter muscles produces muscle weakness and impaired occlusion. The membrane polarization rate and action potential decrease primarily in high polarized muscle fibers of the injured muscle. Meanwhile the function of low polarized fibers does not undergo any significant changes.

[Electrogenesis of muscular fibers in the rat masseter muscle proper].

It was established by the method of intracellular lead of membrane rest potentials (MRP) and action potentials (AP) that fibers with high MRP and little overshot are mainly located in superficial layers of the rat masseter muscle proper whereas those with low MRP and high overshot principally in deep layers. Excitability of the cytoplasmic membrane of muscular fibers of both types proved to be related in electrical properties (critical level of depolarization, current threshold). It is suggested that the rat masseter muscle contains a great number of rapid phasic fibers in superficial layers and slow ones in deep layers.