Publications by authors named "N Donaldson"

Background: NSAIDs are commonly used as first line therapy in chronic nonbacterial osteomyelitis (CNO) but are not effective for all patients. The objective of this study was to identify clinical variables associated with NSAID monotherapy response versus requiring second-line medication in a single-center cohort of patients with CNO.

Methods: The charts of children with CNO who attended a CNO clinic at a quaternary care center between 1/1/05 and 7/31/21 were retrospectively reviewed.

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Silicon integrated circuits (ICs) are central to the next-generation miniature active neural implants, whether packaged in soft polymers for flexible bioelectronics or implanted as bare die for neural probes. These emerging applications bring the IC closer to the corrosive body environment, raising reliability concerns, particularly for chronic use. Here, we evaluate the inherent hermeticity of bare die ICs, and examine the potential of polydimethylsiloxane (PDMS), a moisture-permeable elastomer, as a standalone encapsulation material.

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The ability of anthropogenic aerosols to freeze supercooled cloud droplets remains debated. In this work, we present observational evidence for the glaciation of supercooled liquid-water clouds at industrial aerosol hot spots at temperatures between -10° and -24°C. Compared with the nearby liquid-water clouds, shortwave reflectance was reduced by 14% and longwave radiance was increased by 4% in the glaciation-affected regions.

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Objective: To characterize cystometry in conscious and anesthetized sheep, including bladder response to sacral root electrical stimulation, thereby providing a baseline set of values.

Methods: Single-fill cystometries were repeated in adult mule ewes both conscious (n = 5) and under general anesthesia (18) using a commercial system. Parameters including bladder capacity, detrusor (bladder) pressure, urethral opening pressure, bladder compliance, number of nonvoiding detrusor contractions, and bladder pressure change in response to electrical stimulation of the sacral roots under general anesthesia are reported.

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Following Ni-catalysed Suzuki-Miyaura cross coupling reactions, Ni is electrochemically removed on to the cathode, offering potential for recovery and reuse. The electrochemical recovery method, in combination with an analytical method developed for accurate quantification by HPLC, is expected to be broadly applicable to metal recovery following catalysis.

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