Publications by authors named "N Doichinova"

A case is presented of a man with chronic active hepatitis who developed immune hemolytic anemia in the course of a prolonged treatment with Catergen/(+)-Cianidanol-3/Zyma (four therapeutic courses in two years). The possible mechanism of hemolysis during Catergen treatment are discussed. The most probable mechanism is the absorption of the drug on the erythrocytes.

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The immunologic problems of blood transfusion of patients with antoimmune hemolytic anemia are discussed on the base of the authors' observations. They emerge and are mainly conditioned by the character and serological characteristic of autoantibodies (AAB) as well as by the presence of free iso-antibodies (erythro-, leuko- and thrombocyte-). The cold AAB conditioned the difficulties in blood groups determination, direct compatibility test and rarely of RH, where as the warm ones -- impede the determination of Rh and the selection of compatible blood for transfusion.

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