Publications by authors named "N Dobashi"
Article Synopsis
- - This study explored the effectiveness of allogeneic stem cell transplantation (allo-SCT) for patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) who were in their first complete remission (CR1) and achieved complete molecular remission (CMR) within three months.
- - Out of 147 patients analyzed (101 received allo-SCT and 46 did not), results showed that those who underwent allo-SCT had significantly better overall survival (73%) and relapse-free survival (70%) over five years compared to the non-SCT group (50% and 20%, respectively).
- - Although the allo-SCT group experienced higher non-relapse mortality, they had a significantly lower relapse rate, indicating that
Jpn J Clin Oncol
February 2024
Article Synopsis
- The "Otsuka" minor BCR-ABL messenger RNA assay kit was developed for precise assessment of minor BCR-ABL levels in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia (ALL), an important factor for prognosis and treatment planning.
- Testing showed that the "Otsuka" kit performed reliably, with results aligning closely with established methods and demonstrating strong correlations with other diagnostic tests.
- The findings suggest that the "Otsuka" kit could be a significant advancement in understanding and treating Philadelphia chromosome-positive ALL, given its high precision and effectiveness compared to conventional diagnostic tools.
