Publications by authors named "N Demircan"
Background/aim: The Memorial Sloan Kettering Cancer Center (MSKCC) nomogram was developed to predict survivorship in gastric cancer patients undergoing R0 resection. This study aimed to evaluate the predictive power of this nomogram in the Turkish patient population.
Materials And Methods: Gastric cancer patients over 18 years of age who were admitted to our clinic between 2000 and 2019 and underwent primary curative surgery and R0 resection were included in the study.
Article Synopsis
- * Among 106 patients, 83 had CN, and those who had the surgery could continue their nivolumab treatment for longer (14.5 months) compared to those who didn't have the surgery (6.7 months).
- * Overall survival was better for patients with CN (22.9 months) compared to those without it (8.1 months), but the surgery and certain medical scores were important factors for how long they lived.
Article Synopsis
- Heavy metal exposure (Fe, Zn, Cu, As) in Arabidopsis thaliana seedlings led to significant growth reduction (50-70%) and increased unfolded protein accumulation in the endoplasmic reticulum (ER), indicating ER stress.
- Zn, Cu, and As specifically induced the unfolded protein response (UPR) genes, with Zn triggering bZIP28 expression, while Fe did not elicit a similar response.
- The results highlight that heavy metals not only affect growth but also disrupt protein folding and ER function in plants, enhancing our understanding of how metal toxicity impacts plant health.
Electron flow through the electron transport chain (ETC) is essential for oxidative phosphorylation in mitochondria and photosynthesis in chloroplasts. Electron fluxes depend on environmental parameters, e.g.
View Article and Find Full Text PDFManagement and Clinical Outcomes of Eyes With Posterior Segment Intraocular Foreign Bodies Seen at a Tertiary Referral Center.
Ophthalmic Surg Lasers Imaging Retina
August 2024
Background And Objective: This study aimed to identify the prognostic factors regarding the visual and anatomic outcomes of eyes with posterior segment intraocular foreign body (PS-IOFB).
Patients And Methods: The medical records of 95 patients who underwent pars plana vitrectomy and PS-IOFB removal between 2004 and 2021 were retrospectively reviewed. Data on anatomical and visual outcomes, as well as preoperative, intraoperative, and postoperative variables were statistically analyzed.