Exploring Prevalence and Sociodemographic Factors Associated With Smoking Among Malaysian Adults: A Cross- Sectional Study.

Background And Aims: The Malaysian government has implemented various antismoking measures to reduce the incidence of unhealthy lifestyles within the population. This study analyzes the baseline data of the Prospective Urban Rural Epidemiology (PURE) study to establish the prevalence of sociodemographic factors that are associated with smoking habits among Malaysian adults.

Methods: This study was carried out in urban and rural communities with adults aged between 35 and 70 years using purposive sampling.

Gold nanoparticles mediate suppression of angiogenesis and breast cancer growth via MMP-9/NF-κB/mTOR and PD-L1/PD-1 signaling: integrative in vitro validation and network pharmacology insights.

Gold nanoparticles (AuNPs) have emerged as promising candidates for cancer therapy due to their unique physicochemical properties and biocompatibility. In this study, we investigate the synthesis, characterization, and therapeutic potential of AuNPs in breast cancer treatment. Further, it establishes a comprehensive understanding of the mechanisms by which AuNPs suppress angiogenesis and breast cancer growth, identifying novel targets and signaling nodes contributing to the anti-tumor effects of AuNPs.

Vancomycin-resistant Staphylococcus aureus endangers Egyptian dairy herds.

The emergence of pandrug-resistant (PDR) and extensive drug-resistant (XDR) methicillin-resistant and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA) isolates from bovine milk samples along with biofilm formation ability and harboring various virulence genes complicates the treatment of bovine mastitis and highlights the serious threat to public health. This study investigated for the first time the frequency, antimicrobial resistance profiles, biofilm-forming ability, virulence factors, spa and staphylococcal cassette chromosome mec (SCCmec) types of MRSA and VRSA isolated from clinical and subclinical bovine mastitis in Egypt. A total of 808 milk samples were collected from each quarter of 202 dairy animals, including 31 buffaloes and 171 cattle.

Do Routine Postoperative Radiographs Influence the Management of Distal Radius Fractures Following Volar Locking Plate Fixation?

Background: Distal radius fractures (DRFs) are a common orthopaedic injury, often requiring surgical intervention. Routine postoperative radiographs are frequently obtained after surgical fixation to ensure adequacy of fixation and rule out early complications, yet their necessity remains unclear. Through this study, we tried to evaluate the impact of routine postoperative radiographs on the management of DRFs.