Publications by authors named "N DeBono"
Article Synopsis
- Contemporary asbestos exposure is now primarily linked to construction and maintenance work involving asbestos-containing materials (ACM), with the Ontario Asbestos Workers Register (AWR) created in 1986 to track exposure among workers.* -
- A study linked 26,204 AWR registrants to health databases, revealing elevated rates of asbestos-related diseases (ARD) like mesothelioma and pulmonary fibrosis, particularly among those with longer exposure times.* -
- Despite Canada banning asbestos in new products, existing ACM still poses a risk during construction activities, emphasizing the need for continued monitoring of asbestos-related health issues.*
Leukemia Incidence by Occupation and Industry: A Cohort Study of 2.3 Million Workers from Ontario, Canada.
Int J Environ Res Public Health
July 2024
Although a significant body of evidence has attributed certain occupational exposures with leukemia, such as benzene, formaldehyde, 1,3-butadiene and ionizing radiation, more research is needed to identify work environments at increased risk for this disease. Our study aimed to identify occupational and industry groups associated with an elevated incidence of leukemia using a diverse cohort of workers' compensation claimants from Ontario, Canada. A total of 2,363,818 workers in the Occupational Disease Surveillance System (ODSS) cohort, with claims between 1983-2019, were followed for malignant leukemia diagnoses up to 31 December 2019.
View Article and Find Full Text PDFBackground: A retrospective cohort study was conducted to estimate associations between an ultrafine aluminum powder, McIntyre Powder (MP), and cardiovascular disease incidence in a cohort of mine workers from Ontario, Canada. Disease outcomes included ischemic heart disease (IHD), acute myocardial infarction (AMI), congestive heart failure (CHF), and strokes and transient ischemic attacks (STIA).
Methods: Using work history records from the Ontario Mining Master File (MMF) mine workers were followed for disease incidence in administrative health records.
Objectives: To summarise the rationale, workflow and recommendations for the conduct of exposure assessment critiques in key human studies evaluated for International Agency for Research on Cancer (IARC) on the Identification of Carcinogenic Hazards.
Methods: Approaches to evaluating exposure assessment quality in human cancer and mechanistic studies were reviewed according to the precepts outlined in the IARC Preamble, using two agents as case studies. Exposure assessment 'domains', that is, salient aspects of exposure assessment for the agent under evaluation, were selected for review across the key human studies.
Article Synopsis
- The study aimed to explore cancer risk in Ontario's workforce by comparing cancer rates using both internal (ODSS workers) and external (general population) reference groups.
- Researchers analyzed data from about 2.3 million workers with compensation claims to calculate standardized incidence ratios (SIRs) for various cancer types from 1983 to 2018.
- Results showed that SIRs were usually similar or lower when compared to the general population, revealing differences in cancer rates depending on the reference group used, highlighting the significance of reference group selection in occupational cancer risk evaluations.