[The impact of regular physical activity on physical and mental health: how motivate the patient?].

A sedentary lifestyle is associated with the development of numerous diseases and seems to increase in western societies. The influence of a regular physical activity in the prevention of cardiovascular diseases, diabetes, obesity, cancers, anxious and depressive disturbances is summarized. Potential mechanisms of its positive influence are discussed and prescription recommendations are made.

Efficacy of cisapride in functional dyspepsia resistant to domperidone or metoclopramide: a double-blind, placebo-controlled study.

A double-blind, placebo-controlled trial was performed to determine the therapeutic efficacy of cisapride in patients with refractory functional dyspepsia. A total of 147 patients with functional dyspepsia characterized by prominent epigastric pain or discomfort were randomized to 2 weeks' treatment with metoclopramide or domperidone (both 30 mg/day); of these, 53 patients unresponsive to dopamine antagonist treatment were randomized to cisapride 30 mg/day or placebo for an additional 2 weeks. Metoclopramide and domperidone produced comparable alleviation of epigastric symptoms; global efficacy was good or excellent in 62% and 57% of patients, respectively.