Glucose Homeostasis in Relation to Neutrophil Mobilization in Smokers with COPD.

Purpose: Type 2 diabetes mellitus (T2DM) and metabolic syndrome (MetS) are common comorbidities in chronic obstructive pulmonary disease (COPD), but the underlying pathogenic mechanisms are poorly understood. Given that these morbidities all display increased neutrophil mobilization, the current study aimed to address whether glucose homeostasis relates to signs of neutrophil mobilization in COPD.

Methods: The study population included healthy non-smokers (HNS) and long-term smokers without (LTS) and with COPD (LTS+COPD).

Mucin Binding to during Airway Inflammation Is Dependent on Sialic Acid.

Chronic obstructive pulmonary disease (COPD) is associated with colonization by bacterial pathogens and repeated airway infections, leading to exacerbations and impaired lung function. The highly glycosylated mucins in the mucus lining the airways are an important part of the host defense against pathogens. However, mucus accumulation can contribute to COPD pathology.

Heart rate strain indices in Greek steelworkers.

The heart rate strain of 14 Greek steelworkers was assessed during the winter and summer months of 1989 and 1990. Activity sampling was used to establish the pattern of work performed and heart rates were measured throughout work shifts. In addition, maximum aerobic capacity was estimated.

Sudden death of a young wrestler during competition.

The circumstances of the sudden death of a young healthy wrestler in the course of a wrestling match are described. The death occurred due to acute ischemia of the brainstem as a result of the acute interruption of blood flow to his vertebral-basal system, as a consequence of the injury or rupture of vertebral arteries, after injury of the neck. This interruption of the irrigation of the brainstem with blood provoked the sudden death of the athlete.