Publications by authors named "N D Lehner"

Article Synopsis
  • The Pharma Proteomics Project is a large-scale research initiative analyzing blood protein profiles from over 54,000 UK Biobank participants to understand links between genetics and health.
  • The project identifies significant genetic associations with proteins, revealing many novel interactions and highlighting ancestry-specific variations, along with insights into disease mechanisms and potential drug targets.
  • By making their findings publicly accessible, the consortium aims to advance research in biomarker development and therapeutic strategies, enhancing our understanding of how genetic factors influence health outcomes.
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Objectives: Although the vast majority of COVID-19 cases are treated in primary care, patients' experiences during home isolation have been little studied. This study aimed to explore the experiences of patients with acute COVID-19 and to identify challenges after the initial adaptation of the German health system to the pandemic (after first infection wave from February to June 2020).

Methods: A mixed-method convergent design was used to gain a holistic insight into patients experience.

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The Large Magellanic Cloud (LMC) and the Small Magellanic Cloud (SMC) are the closest massive satellite galaxies of the Milky Way. They are probably on their first passage on an infalling orbit towards our Galaxy and trace the continuing dynamics of the Local Group. Recent measurements of a high mass for the LMC (M ≈ 10 M) imply that the LMC should host a Magellanic Corona: a collisionally ionized, warm-hot gaseous halo at the virial temperature (10 K) initially extending out to the virial radius (100-130 kiloparsecs (kpc)).

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The primordial abundances of light elements produced in the standard theory of Big Bang nucleosynthesis (BBN) depend only on the cosmic ratio of baryons to photons, a quantity inferred from observations of the microwave background. The predicted primordial (7)Li abundance is four times that measured in the atmospheres of Galactic halo stars. This discrepancy could be caused by modification of surface lithium abundances during the stars' lifetimes or by physics beyond the Standard Model that affects early nucleosynthesis.

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Outflowing winds of multiphase plasma have been proposed to regulate the buildup of galaxies, but key aspects of these outflows have not been probed with observations. By using ultraviolet absorption spectroscopy, we show that "warm-hot" plasma at 10(5.5) kelvin contains 10 to 150 times more mass than the cold gas in a post-starburst galaxy wind.

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