Publications by authors named "N D Kuchma"
Article Synopsis
- The study aimed to assess the effectiveness of adding bezlotoxumab to repeat fecal microbiota transplantation (FMT) for patients with recurrent Clostridioides difficile infections after a previous unsuccessful FMT.
- It was found that combining bezlotoxumab with a second FMT significantly increased the cure rate from 48% to 89%.
- The research highlights the importance of understanding how bezlotoxumab and FMT work together and suggests that similar strategies could apply to other treatments for preventing C. difficile infection recurrence.
Objective: The aim of the article is to analyze demographic indicators, clinical symptoms, concomitant pathology, and the course of acute respiratory viral infection (ARVI) caused by SARS-CoV-2 in patients with a fatal outcome of the disease.
Patients And Methods: Materials and methods: To achieve the goal, a statistical method, an analytical method, and a method of retrospective analysis of the medical histories of patients with fatal cases who were hospitalized with a diagnosis of ARVI caused by SARS-CoV-2 were used.
Results: Results: Mortality among patients who were hospitalized with a diagnosis of ARVI caused by SARS-CoV-2 was 8.
Objective: The aim of our work was to study the indicators of systemic inflammation in patients with chronic obstructive pulmonary disease (COPD) with anemia of chronic disease (AHD).
Patients And Methods: Materials and methods: The study included 144 COPD patients (1 group) without anemia (hemoglobin> 120 g/l for women and> 130 g/l for men), and 33 patients (2 group) with COPD and ACD (hemoglobin <120 g/l for women and <130 g/l for men, soluble transferrin receptors (sTFR) - 8.7 - 28.
The article presents the results of the study C677T and A1298C polymorphisms of MTHFR gene and their influence on plasma homocysteine levels in patients with nonalcoholic fatty liver disease (NAFLD). The study involved 100 patients with NAFLD and 40 apparently healthy individuals (control group). Determination of allelic polymorphism was performed by polymerase chain reaction with the detection results of hybridization by fluorescence in real-time.
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