Publications by authors named "N D Gladkova"

Article Synopsis
  • The research investigates how different types of glial tumors in rats affect the attenuation coefficient of white matter in the brain, showing varied impacts based on tumor type and malignancy.
  • Some tumors lead to a significant drop in this coefficient due to cell infiltration and damage to myelinated fibers, while others compress fibers without major destruction.
  • The study also highlights the potential of using the attenuation coefficient, derived from OCT data, to identify late radiation damage in white matter, suggesting its usefulness for evaluating tissue health around tumors during surgeries.
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Unlabelled: The condition of gastrointestinal tract determines in many respects the regenerative capacity and the risk of complications in patients with extensive skin burns. However, the mechanism of developing vascular dysfunction in the colon in the burned individuals has so far been poorly studied. is to study intramural circulatory disorders of the colon using optical coherence tomography angiography (OCTA) and laser Doppler flowmetry (LDF) in different time periods after modeling a thermal burn.

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: The most important phase in the endometrial pathologies diagnostics is the histological examination of tissue biopsies obtained under visual hysteroscopic control. However, the unclear visual diagnostics characteristics of subtle focal endometrial pathologies often lead to selection errors regarding suspicious endometrial lesions and to a subsequent false pathological diagnosis/underestimation of precancer or early-stage cancer. : In this study, we investigate the potential of Multimodal Optical Coherence Tomography (MM OCT) to verify suspicious endometrial lesion regions before biopsy collection.

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While cryotherapy is one of the traditional ways to reduce postoperative complications in maxillofacial surgery, the cooling degree is not regulated in most cases and the achieved effect is not properly controlled. Therefore, to develop optimal cooling modes, we propose to study the buccal vascular response to cooling, which has not been previously shown. To evaluate the effect of cooling, we analyzed vessel networks using optical coherence tomography angiography (OCT-A).

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Article Synopsis
  • - The study introduces a new use of compression optical coherence elastography (C-OCE) to track damage in small intestine layers of minipigs (n = 36) as they are stretched.
  • - C-OCE measured the stiffness of different intestine wall layers and identified a significant drop in stiffness in the longitudinal muscular layer at 25% elongation, indicating potential tears.
  • - The results suggest that C-OCE could effectively predict safe stretching limits of intestinal tissues, which could be crucial for preventing ruptures during medical procedures.
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