Publications by authors named "N D Egorova"

Objective: Postoperative delirium remains a common complication after cardiac surgery in high-risk patients and has been associated with prolonged intensive care unit length of stay, overall morbidity, and mortality. It has been proposed that cerebral hypoperfusion is an important etiological component. In the present study, we retrospectively queried intraoperative near-infrared spectroscopy measurements of regional cerebral oxygen saturations (rSO) during adult cardiac surgical procedures to examine the association between rSO desaturations and postoperative delirium.

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Objective: Hemoconcentration and cell saver use are blood conservation techniques that are often used in cardiac surgery to salvage the patient's own blood to reduce autologous transfusion. The purpose of this study was to examine the perioperative outcomes including transfusion rates in cardiac surgical patients receiving hemoconcentrated blood versus cell saver blood via retrospective chart review. We hypothesized that hemoconcentration would have better patient outcomes, including reduced transfusion rates, compared to only cell salvage technique.

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Background: Despite the widespread use of pulse oximetry for intraoperative estimation of arterial oxygen saturation, there is growing evidence that certain patient populations may be vulnerable to inaccurate pulse oximetry measurements and that unrecognized hypoxemia is associated with end-organ damage and adverse outcomes. In this single-center retrospective cohort study, we sought to better elucidate the relationship between intraoperative occult hypoxemia and postoperative mortality among patients undergoing anesthesia and surgery.

Methods: Data were collected from our departmental data warehouse for adult patients (≥18 years) undergoing anesthesia between 2008 and 2019 with at least 1 intraoperative arterial blood gas recorded.

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Article Synopsis
  • Anesthetic gases are linked to global warming, prompting a project to analyze their carbon dioxide equivalent (CDE) production and fresh gas flows (FGF) in the operating room over two years.
  • In the second year, individualized feedback through a dashboard significantly reduced median FGF from 2.0 to 1.9 l/min and total CDE from 5.10 to 3.59 kg/hr (both p < 0.001).
  • The intervention resulted in notable reductions in CDE for isoflurane and nitrous oxide, leading to faster declines in their usage rates, although it showed no significant impact on sevoflurane or nitrous oxide CDE rates.
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Objective: The study objective was to characterize the trends and outcomes of aortic valve replacement in patients aged less than 65 years with aortic stenosis between 2013 and 2021.

Methods: This retrospective analysis included 9557 patients who underwent biological aortic valve replacement in California, New York, and New Jersey from 2013 to 2021. Patients were stratified by approach: transcatheter aortic valve replacement versus surgical aortic valve replacement.

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