Publications by authors named "N D'Onofrio"
Purpose: To evaluate the intermediate-term visual and safety outcomes of the small-incision second-generation implantable miniature telescope (SING IMT) in patients with late-stage age-related macular degeneration (AMD) at 6 months post-surgery.
Design: Retrospective cohort study.
Methods: Medical records of patients implanted with the SING IMT at two sites in Italy were reviewed.
Our objective is to determine the protein and complements constituents of Cord blood Platelet-rich plasma (CB-PRP), based on the hypothesis that it contains beneficial components capable of arresting or potentially decelerating the advancement of atrophic age-related macular degeneration (dry-AMD), with the support of radiomics. Two distinct pools of CB-PRP were assessed, each pool obtained from a total of 15 umbilical cord-blood donors. One aliquot of each pool respectively was subjected to proteomic analysis in order to enhance the significance of our findings, by identifying proteins that are shared between the two sample pools and gaining insights into the pathways they are associated with.
View Article and Find Full Text PDFArticle Synopsis
- The rise of plastic pollution is a serious global issue that poses both environmental and health risks, particularly due to microplastics (MPs) and nanoplastics (NPs) released from degrading plastics.
- Humans are regularly exposed to these tiny particles through ingestion, inhalation, and skin contact, leading to potential health impacts, especially in vital systems like cardiovascular, nervous, reproductive, and digestive systems.
- This review compiles the latest research on the toxic effects of micro- and nanoplastics in human health, aiming to increase awareness and support the development of strategies to combat this ongoing plastic crisis.
Purpose: To report three cases of Smaller-Incision New-Generation Implantable Miniature Telescope (SING-IMG) explantation and three-piece acrylic intraocular lens (IOL) implantation in patients affected by late-stage dry AMD.
Methods: This is a single-center cohort study. Three patients with stable dry AMD previously implanted with SING-IMT failed to adapt to the device requesting its explantation.
Purpose: To examine whether the extension of retinal pigment epithelium (RPE) and outer retinal atrophy (RORA) and various other morphofunctional parameters correlate with the genetic assessment and severity of retinitis pigmentosa (RP).
Methods: Thirty-eight patients (76 eyes) with RP were prospectively enrolled and underwent full ophthalmic examination, including visual field testing, full-field electroretinography (ERG), and optical coherence tomography angiography. The severity of the disease was calculated using the RP stage scoring system, and the area of RORA was assessed using the automatically calculated area of sub-RPE illumination.