Publications by authors named "N Colaianni"
Article Synopsis
- Increasing biological nitrogen fixation (BNF) in maize can lessen the environmental harm caused by synthetic nitrogen fertilizers, but high levels of reactive nitrogen in the rhizosphere hinder this process.
- Researchers developed gene-edited strains of bacteria (Klebsiella variicola and Kosakonia sacchari) to enhance BNF and ammonium release in nitrogen-rich conditions.
- Experiments showed that these engineered strains significantly boosted BNF activity and ammonium output, contributing an average of 21 kg of nitrogen per hectare to maize plants, thus potentially reducing reliance on synthetic fertilizers and improving crop yield stability.
HIV-1 infection within the central nervous system (CNS) includes evolution of the virus, damaging inflammatory cascades, and the involvement of multiple cell types; however, our understanding of how Env tropism and inflammation can influence CNS infectivity is incomplete. In this study, we utilize macrophage-tropic and T cell-tropic HIV-1 Env proteins to establish accurate infection profiles for multiple CNS cells under basal and interferon alpha (IFN-α) or lipopolysaccharide (LPS)-induced inflammatory states. We found that macrophage-tropic viruses confer entry advantages in primary myeloid cells, including monocyte-derived macrophage, microglia, and induced pluripotent stem cell (iPSC)-derived microglia.
View Article and Find Full Text PDFUnlabelled: High flow nasal cannula (HFNC) is used to treat acute hypoxemic respiratory failure (AHRF) even outside the ICU and the ROX index (pulse oximetry/fraction of inspired oxygen/respiratory rate) may predict HFNC failure.
Objective: The purpose of this investigation was therefore to verify whether the ROX index is an accurate predictor of HFNC failure for COVID-19 patients treated outside the intensive care unit (ICU) and to evaluate the validity of the previously suggested threshold.
Design: Multicenter study.
Plants have an innate immune system to fight off potential invaders that is based on the perception of nonself or modified-self molecules. Microbe-associated molecular patterns (MAMPs) are evolutionarily conserved microbial molecules whose extracellular detection by specific cell surface receptors initiates an array of biochemical responses collectively known as MAMP-triggered immunity (MTI). Well-characterized MAMPs include chitin, peptidoglycan, and flg22, a 22-amino acid epitope found in the major building block of the bacterial flagellum, FliC.
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