Publications by authors named "N Clayton Silver"

Background: Plasma cell-free Human Papillomavirus DNA (cfHPVDNA) is a biomarker for oropharyngeal carcinoma. Existing diagnostics may be limited by inadequate sensitivity or high cost/complexity for longitudinal monitoring.

Objectives: We hypothesized that sensitive and specific plasma cfHPVDNA detection may be achieved via a highly-multiplex qPCR method.

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Article Synopsis
  • Despite the growth in vaping, most nicotine cessation research still focuses on traditional cigarette smoking, creating a gap in understanding the unique challenges faced by those quitting vaping.
  • This study aims to analyze discussions from various subreddit forums dedicated to quitting vaping in order to gain insight into the experiences and needs of individuals looking to stop using e-cigarettes.
  • The findings reveal that many posts emphasized seeking and providing social support during the quitting process, with a notable increase in post discussions during the 2019 vaping lung injury crisis; posts about withdrawal symptoms were also frequently mentioned.
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Many of the guidelines that are generally accepted as main operating room best practices are not evidence based. They are based on the concept that if some sterility is good, more must be better. They are not derived from evidence-based sterility.

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Objective: Minor salivary gland carcinomas are challenging to study due to their rarity and heterogeneity. We aim to further characterize clinical characteristics, treatment, and outcomes over 20 years within a single institution.

Study Design: Retrospective chart review was conducted on 210 patients who received primary treatment for minor salivary gland malignancy from 2000 to 2022.

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Background: Head and neck cancer (HNC) patients often have dysphagia following surgical and/or chemoradiation treatment, which can lead to reduced quality of life. Some patients suffer from decreased tongue strength and mobility that may cause discomfort and difficulty with swallowing. Our group has developed a patented genioglossus muscle strength trainer (GMST) to increase tongue protrusive force that has been used in patients with sleep apnea.

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