Management of life-threatening malignant central airway obstruction: A novel approach of using extracorporeal membrane oxygenation with tumor debulking and stenting.

Extracorporeal membrane oxygenation (ECMO) is an artificial lung or heart used to oxygenate and circulate blood. Veno-venous ECMO is most commonly used as an emergency therapy in patients with acute respiratory distress syndrome (ARDS), but it has the potential to be useful in other respiratory-related diseases. We report a case where ECMO successfully allowed for interventional pulmonary procedures in a patient with life-threatening tracheal obstruction secondary to lung cancer, requiring tumor debulking and silicone Y stent placement.

Arginine vasotocin affects motivation to call, but not calling plasticity, in Cope's gray treefrog Hyla chrysoscelis.

The ability to respond to competition is critical for social behaviors involved in mating, territoriality and foraging. Physiological mechanisms of competitive social behaviors may determine not only baseline behavior, but possibly also the plasticity of the response to competition. We examined the effects of the neuropeptide arginine vasotocin (AVT), which is implicated in social behavior in non-mammalian vertebrates, on both spontaneous acoustic advertisement calling behavior and the plastic response to a simulated competitive challenge in Cope's gray treefrogs, Hyla chrysoscelis.

Gastrointestinal tract antigenic profile of cotton-top tamarin, Saguinus oedipus, is similar to that of humans with inflammatory bowel disease.

As an animal model for human inflammatory bowel disease and colorectal cancer, the cotton-top tamarin remains controversial. Demonstration of antigenic similarity to the human would enhance its validity. Using colonic extracts and washings, we compared binding of seven monoclonal antibodies reactive with bowel and cancer antigens in both tamarins and humans with inflammatory bowel disease.

Carcinoembryonic antigen family of adhesion molecules in the cotton top tamarin (Saguinus oedipus).

Humans and the cotton top tamarin, a model for colitis and colorectal cancer, share carcinoembryonic antigen (CEA) moieties. We quantified CEA in colonic washings and extracts in both, and CEA bands were confirmed by Western blot. We compared CEA-family expression in tissues and serum in the tamarin with that of the common marmoset, which develops colitis but not cancer.