Considerations on some anatomo-clinical phenomena of thyroid cancer. Treatment and prognosis. Personal experience with 1515 operated cases.

The authors present a retrospective study on 1515 histologically confirmed cases of thyroid cancer encountered along a period of 30 years of activity. These cases were found among 15,200 patients operated on for thyroid disorders. Of these 1515 cases, 1310 were differentiated carcinomas of the follicular, papillary or trabecular type, 156 nondifferentiated carcinomas and 49 medullary carcinomas.

Surgical indications in endemic goiter. Pre- and postoperative care.

The authors express their opinion with respect to anatomo-clinical forms of endemic goiter. First they suggest preoperative thyroid re-equilibration to avoid postoperative complications such as hypothyroidism or recurrence. Then operative indications for endocrine goiter, especially in an endemic area are discussed.

The thyroglobulin variations during the thyroid surgery for polynodular goiter, hyperthyroidism and cancer.

A radioimmunoassay (RIA) double antibody system for human thyroglobulin (Tgl) was developed with a sensitivity of 2.5 ng/ml T3 and T4 did not interfere in the antibody Tgl binding. The blood was collected pre-, intra- and 24 hrs post-thyroidectomy from 50 females and 4 males diagnosed as polynodular goiter, hyperthyroidism, chronic thyroiditis and thyroid cancer.