Publications by authors named "N Cereb"
Article Synopsis
- Researchers studied how genetic variation affects vaccine responses in infants from African countries, finding specific HLA associations with antibody responses to vaccines like pertussis and hepatitis B.
- They used genetic data from over 1,700 individuals to identify patterns in HLA types that could explain up to 10% of the response variability in infants to these vaccines.
- The study highlighted differences in immune responses based on ancestry, indicating that understanding HLA-DRB1 expression could help refine vaccine design for better effectiveness in diverse populations.
Background: Although there are many possible causes for cervical dystonia (CD), a specific etiology cannot be identified in most cases. Prior studies have suggested a relationship between autoimmune disease and some cases of CD, pointing to possible immunological mechanisms.
Objective: The goal was to explore the potential role of multiple different immunological mechanisms in CD.
The HLA-B*53:69 allele differs from HLA-B*53:01:01:01 by two nucleotide changes in exon 3.
View Article and Find Full Text PDFBetween January 2018 and June 2021, the Ezer Mizion recruited 223,960 donors. All donors were typed for their HLA class I and II alleles at high resolution by Next Generation Sequencing techniques. Comparison between the sequences obtained from these donors and those in the IPD-IMGT/HLA Database, revealed 122 Novel HLA alleles that were found in 133 donors.
View Article and Find Full Text PDFA nucleotide mutation in codon 75 of HLA-C*04:01:01:01 results in a novel allele HLA-C*04:279N.
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