Publications by authors named "N Celejewska-Wojcik"

Purpose: Obstructive sleep apnea (OSA) is associated with many long-term health consequences. We hypothesized that previously unrecognized and untreated OSA may be associated with more severe respiratory failure in hospitalized patients with COVID-19.

Methods: Patients hospitalized in the Pulmonology Department with confirmed COVID-19, University Hospital in Kraków, Poland, between September 2020 and April 2021 were enrolled.

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Background: The cellular inflammatory pattern of nonsteroidal anti-inflammatory drug-exacerbated respiratory disease (N-ERD) is heterogeneous. However, data on the heterogeneity of non-eosinophilic asthma (NEA) with aspirin hypersensitivity are scanty. By examination of N-ERD patients based on clinical data and eicosanoid biomarkers we aimed to identify NEA endotypes potentially guiding clinical management.

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Introduction: Hemostatic abnormalities play an important role in the pathogenesis of COVID‑19 and are considered determinants of the patients' outcomes. Less is known about the dynamics of these abnormalities in a short‑term observation.

Objectives: The aim of the study was to evaluate hemostatic activity markers in patients hospitalized for COVID‑19 depending on the severity of respiratory failure.

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Article Synopsis
  • - COVID-19 patients have an increased risk of blood clots, showing lower levels of protein C and free protein S, and a higher prevalence of certain antibodies compared to controls.
  • - The study involved analyzing blood samples from 118 COVID-19 patients and 46 controls, focusing on thrombin generation and other clotting factors, all taken before any treatment was given.
  • - Pulmonary embolism (PE) occurred in 11% of patients, linked to elevated D-dimer levels, higher troponin I levels, and quicker thrombin peak times during their hospital stay.
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