Publications by authors named "N Carmona-Vicente"
Article Synopsis
- Fecal-orally transmitted gastroenteritis viruses, especially human noroviruses, are a major public health issue linked to contaminated water, but their infectivity has been hard to measure in lab settings.
- This study tested the human intestinal enteroids (HIE) model to evaluate the infectivity of various gastroenteritis viruses in wastewater, finding that this method efficiently supported viral replication without needing complex sample handling.
- Of the 28 wastewater samples tested, 57% showed viral replication, with multiple viral types coexisting in some samples, demonstrating the HIE model's effectiveness in identifying infectious gastroenteritis viruses in real-world wastewater.
Rotavirus (RV) is the leading cause of acute gastroenteritis (AGE) in children under 5 years old worldwide, and several studies have demonstrated that histo-blood group antigens (HBGAs) play a role in its infection process. In the present study, human stool filtrates from patients diagnosed with RV diarrhea (genotyped as P[8]) were used to infect differentiated Caco-2 cells (dCaco-2) to determine whether such viral strains of clinical origin had the ability to replicate in cell cultures displaying HBGAs. The cell culture-adapted human RV Wa model strain (P[8] genotype) was used as a control.
View Article and Find Full Text PDFNoroviruses are the leading cause of sporadic cases and outbreaks of viral gastroenteritis. For more than 20 years, most norovirus infections have been caused by the pandemic genotype GII.4, yet recent studies have reported the emergence of recombinant strains in many countries.
View Article and Find Full Text PDFArticle Synopsis
- Using saliva samples for SARS-CoV-2 testing offers easier collection and potential for large-scale screening.
- Two rapid antigen tests, DIAGNOS™ and Rapid Response™, were evaluated for their accuracy in detecting the virus in saliva.
- DIAGNOS demonstrated higher sensitivity than Rapid Response, making it a promising tool for identifying COVID-19 cases, though additional validation with more samples is needed.