Publications by authors named "N Capkova"
Background: Evidence on the impact of complex neighborhood environment, including air pollution, greenness, and neighborhood socioeconomic deprivation (nSED) on cognitive health in older adults remains scarce. Both cognition and neighborhood environment are associated with physical activity, but little is known about the potential mediating role of physical activity in this association.
Methods: Cross-sectional data of the Czech arm of the HAPIEE cohort study examined 4,178 participants (55.
Article Synopsis
- - The study investigates the relationship between the FTO gene polymorphism (specifically rs17817449) and COVID-19 mortality, suggesting that this gene could influence how individuals respond to the virus due to its role in viral viability.
- - Researchers analyzed data from 5,233 individuals aged 63-87, finding that GG homozygotes had a significantly higher risk of death from COVID-19 compared to those with at least one T allele (odds ratio = 2.01, P <0.01).
- - The findings indicate that variations in the FTO gene are a notable factor in predicting mortality from COVID-19, particularly in Caucasian populations, while showing no impact on deaths from other causes.
Background: This study investigates the association between frailty and mortality in Eastern European populations, which remains largely unexplored compared with Western Europe. The aim is to assess the risk of all-cause and cardiovascular mortality associated with varying levels of frailty.
Methods: A prospective multicentre cohort study was conducted, involving random population samples from the Czech Republic, Poland and Lithuania.
Background: Chronic exposure to air pollutants harms human health, and at a geographical level, concentrations of air pollutants are often associated with socioeconomic disadvantage.
Objectives: The aim of this study was to investigate the effects of educational attainment and air pollution on lung function in older adults, and whether air pollution may mediate the effect of education.
Methods: The study included 6381 individuals (mean age 58.
Article Synopsis
- PFASs are synthetic chemicals that accumulate in the environment and human bodies, linked to health risks like metabolic disorders, and this study aimed to explore their impact on blood lipid profiles and metabolic syndrome through data from the 2019 Czech Health Examination Survey.* -
- The study analyzed serum levels of 11 PFASs in 168 participants, revealing that PFHxS and PFDA significantly correlated with total cholesterol and HDL-cholesterol levels, while other lipids and metabolic syndrome showed no significant connections.* -
- The results suggest some PFASs in blood may affect cholesterol levels, particularly PFHxS and PFDA, indicating a potential health concern related to these chemicals, although the overall impact on metabolic syndrome was not