Publications by authors named "N Cambier"
Legged robots are well-suited for deployment in unstructured environments but require a unique control scheme specific for their design. As controllers optimised in simulation do not transfer well to the real world (the infamous sim-to-real gap), methods enabling quick learning in the real world, without any assumptions on the specific robot model and its dynamics, are necessary. In this paper, we present a generic method based on Central Pattern Generators, that enables the acquisition of basic locomotion skills in parallel, through very few trials.
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- Chronic myelomonocytic leukemia (CMML) is a complex blood disorder linked to kidney issues, prompting this study to examine kidney involvement in CMML patients, their treatments, and outcomes.
- In a multicenter retrospective study involving 16 CMML patients with kidney disease, common issues included kidney injury occurring roughly six months post-CMML diagnosis, with significant findings like lysozyme nephropathy and renal infiltration.
- Despite receiving treatment, many patients faced serious kidney complications, and although kidney involvement correlated with higher monocyte counts and treatment eligibility, there was no significant difference in survival rates compared to CMML controls.
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- Momelotinib is the first inhibitor targeting both JAK1, JAK2, and ACVR1, showing benefits in treating symptoms of myelofibrosis (MF), like splenomegaly and anemia.
- A long-term analysis pooled data from three phase 3 studies involving 725 MF patients, with some remaining on momelotinib for over 5 years.
- The treatment had a manageable safety profile, with diarrhea as the most common side effect, and no increase in serious adverse events over time.
Minimal residual disease (MRD) is now a powerful surrogate marker to assess the response to chemotherapy in acute myeloid leukemia (AML). mutation has been associated with adverse outcomes. In this study, we aimed to investigate the impact of status on NPM1 MRD predictive value for survival in a retrospective cohort of AML patients aged over 60 years old treated intensively.
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