[Which factors are associated to hemorrhagic adverse drug events related to antivitamin K?].

Introduction: Hemorrhagic events constitute a major risk for patients on oral anticoagulant therapy.

Patients And Methods: We conducted a prospective survey of all patients taking oral anticoagulants and admitted to the emergency room of Grenoble University Hospital over a period of 10 months. The objective was to identify the causes of drug-induced adverse hemorrhagic events, and whether they were related to health care practices or patient behavior concerning their treatment.

[Hemorrhagic complications of anti-vitamin K].

Adverse events related to oral anticoagulants represent a major public health problem. Hemorrhagic episodes are the most frequent complications and can be life-threatening. A 10 month prospective survey on all cases treated with anti-vitamin K (AVK), and admitted to emergency room of CHU Grenoble, was conducted to identify the hemorrhagic adverse drug events (HADE).