Publications by authors named "N C Lau"
Objective: This study aims to compare the relative sensitivity between scene-independent and scene-dependent eye metrics in assessing trainees' performance in simulated psychomotor tasks.
Background: Eye metrics have been extensively studied for skill assessment and training in psychomotor tasks, including aviation, driving, and surgery. These metrics can be categorized as scene-independent or scene-dependent, based on whether predefined areas of interest are considered.
Recent advances in machine perfusion have revolutionised the field of transplantation by prolonging preservation, permitting evaluation of viability prior to implant and rescue of discarded organs. Long-term perfusion for days-to-weeks provides time to modify these organs prior to transplantation. By using long-term normothermic machine perfusion to facilitate liver splitting and subsequent perfusion of both partial organs, possibilities even outside the clinical arena become possible.
View Article and Find Full Text PDFArticle Synopsis
- The study compares the effectiveness of continuous wound infusion (CWI) of local anesthetic with thoracic epidural analgesia (TEA) for postoperative pain management after pancreaticoduodenectomy (PD).
- Results showed that while TEA provided better pain relief at rest and while coughing on the second postoperative day, CWI was equally effective for overall pain management across the first five days post-surgery.
- CWI allowed for quicker recovery milestones, such as faster bowel movements and diet initiation, along with lower rates of analgesic failure and nausea/vomiting compared to TEA.
Background: Technology use among older adults is increasingly common. Even though there is potential in leveraging technology to help them manage their health, only a small fraction of them use it for health-related purposes.
Objective: This study seeks to understand the perspectives of and experiences with digital health (DH) among older adults in Singapore.
Transposable Elements (TEs) are implicated in aging and neurodegenerative disorders, but the impact of brain TE RNA dynamics on these phenomena is not fully understood. Therefore, we quantified TE RNA changes in aging post-mortem human and mouse brains and in the neurodegenerative disorders Huntington's Disease (HD) and Parkinson's Disease (PD). We tracked TE small RNAs (smRNAs) expression landscape to assess the relationship to the active processing from TE long RNAs (lnRNAs).
View Article and Find Full Text PDF