Publications by authors named "N C Jones"

This paper discusses how harmful practices such as child marriage and female genital mutilation/cutting (FGM/C) can be effectively explored through feminist methodologies that center the lived experiences of girls and young women affected by these issues. Eliminating harmful practices, which are rooted in gender inequality and have myriad life-course consequences for those who experience them, has become a global priority in recent years. However, dominant conceptualizations of the drivers and consequences of child marriage and FGM/C often fail to adequately engage with or reflect adolescent girls' own nuanced experiences and perceptions.

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Background: Noninvasive caries treatments work topically, which may limit efficacy. The authors hypothesized that an alternative approach using mineral-loaded particles designed to target the subsurface of noncavitated caries lesions could be advantageous. This study shows in vitro proof-of-concept.

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Article Synopsis
  • The study investigates the effect of 40-Hz audiovisual stimulation on seizure susceptibility and amyloid-beta plaque levels in 5xFAD mice, a model for Alzheimer's disease.
  • Results showed that this sensory stimulation decreased seizure severity and delayed epileptogenesis, with 5xFAD mice experiencing about a 50% reduction in amyloid pathology compared to those without stimulation.
  • The findings suggest that 40-Hz stimulation may benefit both the reduction of Aβ pathology and possibly influence glial cells, impacting seizure activity, even in mice without amyloid plaques.
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Introduction: Antimicrobial resistance (AMR) is a global problem and is especially threatening for low-and-middle income countries like Bangladesh. The COSTAR (Community-led Solutions to Antimicrobial Resistance) project includes a Randomised Control Trial (RCT) which aims to evaluate the effectiveness of the Community Dialog Approach (CDA) to improve levels of correct and appropriate knowledge and reported practice about antibiotics, antibiotic use, and antibiotic resistance (ABR) from a One Health perspective, among adult community members in 5 selected sub-districts of Cumilla. The CDA is a community engagement approach involving community members in active discussions also known as Community Dialogs (CD), run by local facilitators.

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Unlabelled: This study investigates the interaction of KEIF, the intrinsically disordered N-terminal region of the magnesium transporter MgtA, with lipid bilayers mimicking cell membranes. Combining experimental techniques such as neutron reflectometry (NR), quartz-crystal microbalance with dissipation monitoring (QCM-D), synchrotron radiation circular dichroism (SRCD), and oriented circular dichroism (OCD), with molecular dynamics (MD) simulations, we characterized KEIF's adsorption behavior.

Hypothesis: KEIF undergoes conformational changes upon interacting with lipid bilayers, potentially influencing MgtA's function within the plasma membrane.

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