Publications by authors named "N C Flores"
Introduction: It is crucial to provide a quality educational response to the needs of autistic children across various mathematical domains. However, there is no consensus on which of the early skills have the greatest predictive effect in the short and long term within these domains. Therefore, this research aimed to a) compare early numerical skills and mathematics domains, and 2) analyze the predictive value of early numerical skills into mathematics domains.
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- * In experiments, dinaciclib increased the sensitivity of certain cancer cell lines to radiation but did not significantly affect apoptosis levels or alter certain cellular signaling pathways, suggesting a complex interaction between the drug and radiation.
- * The study highlights how dinaciclib's inhibition of CDK12 leads to reduced BRCA1 levels, which affects DNA repair mechanisms and may contribute to cancer cell aging, proposing a potential personalized treatment approach based on the genetic characteristics of different tumors.
Identification and isolation of antigen-specific T cells for downstream transcriptomic analysis is key for various immunological studies. Traditional methods using major histocompatibility complex (MHC) multimers are limited by the number of predefined immunodominant epitopes and MHC matching of the study subjects. Activation-induced markers (AIM) enable highly sensitive detection of rare antigen-specific T cells irrespective of the availability of MHC multimers.
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