Publications by authors named "N Brockton"
Post-diagnosis adiposity, physical activity, sedentary behaviour, dietary factors, supplement use and colorectal cancer prognosis: Global Cancer Update Programme (CUP Global) summary of evidence grading.
Int J Cancer
August 2024
Article Synopsis
- A systematic review was conducted on factors like body weight, physical activity, and diet, to evaluate their impact on colorectal cancer prognosis, analyzing 167 publications, mostly observational studies.
- The evidence indicated a complex, reverse J-shaped relationship between body mass index and cancer prognosis, but overall evidence quality was conservative due to potential biases.
- Limited-suggestive findings were noted for recreational physical activity and healthy dietary patterns in reducing mortality risks, highlighting the need for more robust studies to develop effective lifestyle recommendations for colorectal cancer patients.
Introduction: This study investigated the association of Vitamin D with tumor characteristics in pre and postmenopausal women.
Patients And Methods: A prospective cohort of 476 women with incident stage I-III breast cancer (BC) in Alberta, Canada comprised the study population. Vitamin D was measured as 25(OH)D concentration in serum samples collected at diagnosis (presurgery and prior to treatment initiation).
Background: Physical activity (PA) is associated with improved health-related quality of life (HRQoL) among women with breast cancer; however, uncertainty remains regarding PA types and dose (frequency, duration, intensity) and various HRQoL measures. A systematic review and meta-analysis of randomized controlled trials was conducted to clarify whether specific types and doses of physical activity was related to global and specific domains of HRQoL, as part of the Global Cancer Update Programme, formerly known as the World Cancer Research Fund-American Institute for Cancer Research Continuous Update Project.
Methods: PubMed and CENTRAL databases were searched up to August 31, 2019.
It is important to clarify the associations between modifiable lifestyle factors such as physical activity and breast cancer prognosis to enable the development of evidence-based survivorship recommendations. We performed a systematic review and meta-analyses to summarise the evidence on the relationship between postbreast cancer diagnosis physical activity and mortality, recurrence and second primary cancers. We searched PubMed and Embase through 31st October 2021 and included 20 observational studies and three follow-up observational analyses of patients enrolled in clinical trials.
View Article and Find Full Text PDFLittle is known about how diet might influence breast cancer prognosis. The current systematic reviews and meta-analyses summarise the evidence on postdiagnosis dietary factors and breast cancer outcomes from randomised controlled trials and longitudinal observational studies. PubMed and Embase were searched through 31st October 2021.
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