Publications by authors named "N Bozan"
Serum Magnesium Concentration in Patients With Bell's Palsy: A Case-Control Study.
Ear Nose Throat J
July 2024
Some conditions such as hyperglycemia, preeclampsia, migraine, inflammation, oxidative stress, and peripheral neuropathy are associated with magnesium deficiency and Bell's palsy. To date, however, studies have not addressed serum magnesium concentration in patients with Bell's palsy. In this article, we hypothesized that these patients may have a decreased serum magnesium concentration compared to healthy controls.
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- The study assessed the impact of Rhinapi nasal spray on allergic rhinitis symptoms among 10,000 participants in Turkey over a 3-week period.
- The treatment led to significant improvements in total symptom scores, quality of life (QoL) scores, and otolaryngological examination scores, with statistically significant changes before and after usage.
- The findings suggest that Rhinapi effectively reduces symptoms of allergic rhinitis and can be considered as an additional treatment option for those affected.
Hereditary hearing loss (HL) is a genetically heterogeneous disorder affecting people worldwide. The implementation of advanced sequencing technologies has significantly contributed to the identification of novel genes involved in HL. In this study, probands of two Turkish families with non-syndromic moderate HL were subjected to exome sequencing.
View Article and Find Full Text PDFSerum levels of heavy metals in patients with Bell's palsy: a case-control study.
Eur Arch Otorhinolaryngol
February 2024
Purpose: The exact etiology of Bell's palsy (BP) remains unknown, while its potential etiopathology includes neuritis and inflammation-related demyelination as in optic neuritis. It has been reported that disruption of heavy metal homeostasis may be associated with the inflammatory process of optic neuritis; therefore, heavy metals may be involved in the pathogenesis of facial nerve neuritis. In this study, we aimed to investigate serum levels of heavy metals including essential elements [iron (Fe), zinc (Zn), copper (Cu), cobalt (Co), and manganese (Mn)], and nonessential elements [lead (Pb) and cadmium (Cd)] in patients with BP.
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- Hearing loss (HL) is a common condition linked to over 200 different genes, prompting researchers to use exome and genome sequencing to find genetic causes in 322 families from Asia and Latin America.
- The study found that variants in the GJB2 gene were present in 58 participants, but these were excluded from further analysis, as were 38 families with syndromic findings, leading to a focus on 212 families for further genetic testing.
- Exome sequencing revealed 78 variants related to HL in 71 families, with a combined detection rate of 40% using both exome and genome sequencing, the latter proving effective in identifying difficult-to-detect variants in specific genetic regions.