Publications by authors named "N Bossini"
Article Synopsis
- Kidney transplant (KT) recipients face a higher risk of cancer-related deaths compared to the general population, with cancer accounting for 32.4% of deaths in a study of 7,373 KT patients from 2003 to 2020.
- The overall excess mortality rate due to cancer was found to be 1.8 times higher, with lymphomas, kidney cancer, and skin melanoma exhibiting the highest risks.
- The study highlights the need for further research into cancer prevention and early detection strategies specifically tailored for KT recipients, given the significant and consistent risks across different age groups.
Article Synopsis
- - The Renal Biopsy for Kidney Transplantation Therapy (ReBIrth) meeting held on May 31, 2022, in Bologna, Italy, focused on advancements in kidney transplantation, bringing together key experts in nephrology, surgery, and pathology.
- - The paper highlights experiences with kidney transplants and aims to report on the histopathological features of failed kidney allografts, analyzed through a digital pathology platform.
- - Findings suggest that digital pathology effectively identifies critical morphological and immunohistochemical traits, potentially enhancing the use of immunosuppressive therapy to reduce graft failure and improve patient care.
This cohort study examined 25-year variations in cancer incidence among 11,418 Italian recipients of kidney transplantation (KT) from 17 Italian centers. Cancer incidence was examined over three periods (1997-2004; 2005-2012; and 2013-2021) by internal (Incidence rate ratio-IRR) and external (standardized incidence ratios-SIR) comparisons. Poisson regression was used to assess trends.
View Article and Find Full Text PDFBackground: Dialysis and kidney transplant patients with moderate-severe COVID-19 have a high mortality rate, around 30%, that is similar in the two populations, despite differences in their baseline characteristics. In these groups, the immunology of the disease has been poorly explored.
Methods: Thirty-two patients on dialysis or with kidney transplant and SARS-CoV-2 infection requiring hospitalization (COV group) were included in our study.
This study assessed the impact of cancer on the risk of death with a functioning graft of kidney transplant (KT) recipients, as compared to corresponding recipients without cancer. A matched cohort study was conducted using data from a cohort of 13 245 individuals who had undergone KT in 17 Italian centers (1997-2017). Cases were defined as subjects diagnosed with any cancer after KT.
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