Publications by authors named "N Boon"
Article Synopsis
- The study examines the effectiveness of flow cytometry as a quick and cost-effective method for determining the composition of synthetic bacterial communities compared to traditional methods like bacterial plating, strain-specific qPCR, and 16S rRNA gene amplicon sequencing.
- Flow cytometry showed a lower average error when quantifying the composition of axenic cultures and mock communities, outperforming both PCR-based methods and sequencing.
- However, when bacteria were co-cultured, the accuracy of all methods decreased, highlighting the difficulties in accurately quantifying community composition due to the changing phenotypes of the bacteria.
Importance: Development of myocardial fibrosis in patients with aortic stenosis precedes left ventricular decompensation and is associated with an adverse long-term prognosis.
Objective: To investigate whether early valve intervention reduced the incidence of all-cause death or unplanned aortic stenosis-related hospitalization in asymptomatic patients with severe aortic stenosis and myocardial fibrosis.
Design, Setting, And Participants: This prospective, randomized, open-label, masked end point trial was conducted between August 2017 and October 2022 at 24 cardiac centers across the UK and Australia.
Recently, there has been increased attention to hydrocarbonoclastic bacteria in the plastisphere. One particular genus, Alcanivorax, is reported in the biodegradation of several polymers in the literature. In this study, we further explored the role of Alcanivorax in the early colonization of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) (PHBH), nylon 6/69, and a novel plastic B4PF01.
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- Metal-organic frameworks (MOFs), like zeolites, are crystalline materials with channels that can effectively adsorb environmental contaminants.
- In this study, a zirconium MOF called UiO-66 was modified with ferrocene to enhance the selective removal of oxyanions such as nitrate (NO), sulfate (SO), and phosphate (PO) from contaminated mixtures.
- The research found that the functionalized MOF exhibited a strong preference for phosphate ions over other contaminants, with the preference linked to the interaction of oxyanions with positively charged sites within the material's pores and the strong bonding to zirconium nodes.
Unlabelled: Antiseptics are widely used in oral healthcare to prevent or treat oral diseases, such as gingivitis and periodontitis. However, the incidence of bacteria being tolerant to standard antiseptics has sharply increased over the last few years. This stresses the urgency for surveillance against tolerant organisms, as well as the discovery of novel antimicrobials.
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