Publications by authors named "N Bonini"
Background: Heart failure (HF) often occurs in patients with atrial fibrillation (AF), with a major impact on prognosis. Few data are available on the effect of integrated treatment strategies to improve prognosis in patients with AF. We aimed to evaluate the association between HF (according to left ventricular ejection fraction [LVEF]), HF optimal medical therapy and adherence to the Atrial Fibrillation Better Care pathway, and major outcomes in patients with AF.
View Article and Find Full Text PDFPeripheral artery disease, antithrombotic treatment and outcomes in European and Asian patients with atrial fibrillation: analysis from two prospective observational registries.
BMC Med
December 2024
Background: In patients with atrial fibrillation (AF), the impact of peripheral artery disease (PAD) on oral anticoagulant (OAC) therapy use and the risk of outcomes remains unclear.
Objective: To analyse the epidemiology of PAD in a large cohort of European and Asian AF patients, and the impact on treatment patterns and risks of adverse outcomes.
Methods: We analysed AF patients from two large prospective observational registries.
Since 1995, the concept of atrial cardiomyopathy (ACM) has been associated with myocardial fibrosis. Despite a consensus document in 2016, ACM's definition primarily relies on histopathological findings. The focus on diagnostic criteria for ACM is driven by the potential link to thromboembolic events even independently on atrial fibrillation (AF).
View Article and Find Full Text PDFArticle Synopsis
- The study investigates if using algorithms for right ventricular pacing modulation (RVPm) can lower negative health outcomes compared to traditional dual-chamber pacing (DDD) in patients needing anti-bradycardia treatments.
- The analysis, which included eight studies and over 7,200 patients, revealed that RVPm was associated with a reduced risk of persistent atrial fibrillation and cardiovascular hospitalizations, but no significant impact on overall mortality or adverse symptoms was found.
- Overall, RVPm algorithms appear beneficial in minimizing certain health risks, without increasing unwanted side effects, even for patients with higher levels of atrioventricular block.