Cometabolism of DDT analogs by a Pseudomonas sp.

A Pseudomonas sp. capable of growth on several nonchlorinated and mono-p-chloro-substituted analogs of DDT as a sole carbon source degraded bis(p-chlorophenyl)methane and 1,1-bis(p-chlorophenyl)ethane only in the presence of diphenylethane. The products p-chlorophenylacetic acid and 2-(p-chlorophenyl)-propionic acid were not further metabolized by the bacterium.

Some observations on biodegradation of pollutants in aquatic systems.

The biodegradability of pollutants introduced into aquatic environments is subject to many variabilities characteristic of microbial processes. Some observations have been reported on studies with p-cresol, methyl parathion, benzo[b]thiophene, dibenzothiophene, 9H-carbazole, quinoline, benzo[f]quinoline, benz[a]anthracene, benzo[a]pyrene, 7H-dibenzo[c,g]carbazole, Mirex, 2,4-dichlorophenoxyacetic acid, Lindane and 1,1-bis(p-chlorophenyl)-2,2,2-trichloroethane analogs. Water reservoirs included a eutrophic stream, a eutrophic pond, an oligotrophic lake and effluents from waste-water treatment plants.

Metabolism of DDT analogues by a Pseudomonas sp.

A Pseudomonas sp. rapidly metabolized several nonchlorinated analogues of DDT, with the exception of 2,2-diphenylethanol, as the sole carbon source. Several of the mono-p-chloro-substituted diphenyl analogues were also metabolized as the sole carbon source by the bacterium.

LL-A491, a monazomycin-like antibiotic.

A new antibiotic, designated LL-A491, was isolated by butanol extraction and crystallization from beers of an unidentified streptomycete, Lederle culture A491. LL-A491 was primarily active against gram-positive bacteria and was related to monazomycin. A tentative molecular formula of C(72+/-2) H(144+/-8) O(25+/-1) N for the antibiotic, based on analyses of the crystalline hydrochloride, picrate, and picrolonate salts, is considerably larger than that proposed for monazomycin, from which LL-A491 was not differentiated by paper chromatography.