Sex Differences in Health-Related Quality of Life in Patients With Head and Neck Cancer-A Prospective Study.

Objective: To analyse sex differences in health-related quality of life (HRQL) before, during and up to 3 months posttreatment of head and neck cancer, and to examine the importance of salivary secretion rate for HRQL posttreatment.

Methods: Patients were recruited before starting curative oncologic treatment. Clinical examinations were performed including determination of the stimulated salivary secretion rate.

Prospective study on health-related quality of life, oral mucositis and oral health on during treatment of head and neck cancer.

Background: Few studies have examined health related Quality of Life (HR-QoL) during the treatment of head and neck cancer (HNC) with even fewer focusing on the impact of oral mucositis (OM) on HR-QoL. Studies performed during treatment of HNC makes it possible to follow fluctuations in HR-QoL, OM and other treatment related side effects. The aim was to prospectively analyze HR-QoL, changes in clinical variables and the impact of OM on HR-QoL during HNC treatment.

The power of language: how to bridge the gap between healthcare research and patients - a scoping review.

Objective: The value of patient involvement to the design, conduct, and outcomes of healthcare research is increasingly being recognized. Patient involvement also provides greater patient accessibility and contribution to research. However, the use of inaccessible and technical language when communicating with patients is a barrier to effective patient involvement.

Characterising meaningful patient and public involvement in the pharmaceutical industry research setting: a retrospective quality assessment.

Objectives: Patient and public involvement (PPI) in clinical research has a well-established infrastructure in the UK, and while there has been good progress within pharmaceutical-industry-sponsored research, further improvements are still needed. This review aims to share learnings from quality assessments of historical PPI projects within Pfizer UK to inform future projects and drive PPI progress in the pharmaceutical industry.

Design And Setting: Internal assessments of Pfizer UK PPI projects were conducted to identify all relevant projects across the medicines development continuum between 2017 and 2021.

Analysis of ballistic transport and resonance in the α-Fermi-Pasta-Ulam-Tsingou model.

Ballistic transport and resonance phenomena are elucidated in the one-dimensional α-Fermi-Pasta-Ulam-Tsingou (FPUT) model using an approach of computing thermal response functions. The existence of periodic oscillations in spatially sinusoidal temperature profiles seen in previous studies is confirmed. However, the results obtained using response functions enable a more complete understanding.