Publications by authors named "N Bloom"

A country's national income broadly depends on the quantity and quality of workers and capital. But how well these factors are managed within and between firms may be a key determinant of a country's productivity and its GDP. Although social scientists have long studied the role of management practices in shaping business performance, their primary tool has been individual case studies.

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In recent decades, economic activity has become increasingly concentrated in major global metropolises. Yet, the rise of working from home threatens this dominance of cities. Using multiple high-frequency datasets on spending, commuting, migration, and housing, we provide global evidence that remote work has dispersed economic activity away from city centers.

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Context: Majority of research surrounding the predictive value of clinical measurements and assessments for future athletic injury does not differentiate between contact and non-contact injuries.

Objective: We assessed the association between clinical measures and questionnaire data collected prior to sport participation and the incidence of non-contact lower extremity (LE) injuries among Division III collegiate athletes.

Design: Prospective cohort study.

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The induction of durable protective immune responses is the main goal of prophylactic vaccines, and adjuvants play an important role as drivers of such responses. Despite advances in vaccine strategies, a safe and effective HIV vaccine remains a significant challenge. The use of an appropriate adjuvant is crucial to the success of HIV vaccines.

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Article Synopsis
  • Therapeutic monoclonal antibodies (mAbs), specifically bamlanivimab targeting the SARS-CoV-2 spike protein, have been shown to alter the memory B cell (MBC) responses in individuals already infected with the virus.
  • The treatment skewed MBCs to favor non-receptor binding domain (RBD) epitopes, resulting in a weaker affinity for RBD memory B cells compared to those who received a placebo.
  • Even after mRNA COVID-19 vaccination, these changes persisted, indicating that mAb treatment can have lasting effects on immune memory and how the immune system recognizes specific viral epitopes.
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