Publications by authors named "N Bisi"

Background: The suprageniculate fossa (SGF) is located between the geniculate ganglion, the middle cranial fossa (MCF) and the anterior semicircular canal (ASCC). An endoscopic transcanal approach has been recently proposed to treat the different lesions in this area. The aim of the study is to describe the anatomical pathway of this approach by measuring the dimensions of its boundaries while checking their correlation with the pneumatization of the SGF area.

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: Petrous apex cholesterol granulomas (PACGs) are benign inflammatory cystic lesions of the temporal bone. Usually, asymptomatic patients may develop symptoms as the lesions expand. The diagnosis is based on both CT and MRI scans and the management relies on "wait and scan" or surgery.

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Tauopathies such as Alzheimer's disease are characterized by aggregation and increased phosphorylation of the microtubule-associated protein tau. Tau's pathological changes are closely linked to neurodegeneration, making tau a prime candidate for intervention. We developed an approach to monitor pathological changes of aggregation-prone human tau in living neurons.

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Article Synopsis
  • Alzheimer's Disease (AD) and Parkinson's Disease (PD) are major neurodegenerative diseases characterized by the misfolding and aggregation of amyloid proteins, leading to neurotoxicity and cell death.
  • Currently, these diseases can only be diagnosed after significant neuronal damage occurs, making early detection and effective treatment difficult.
  • The article emphasizes the urgent need for selective probes that can accurately identify early toxic amyloid species and reviews existing research on compounds that target these aggregates, along with challenges in translating these findings into clinical practice.
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Many techniques have been proposed to restore facial symmetry in facial nerve palsies. This study presents our surgical approach called Endoscopic Temporalis Tendon Extension (ETTE). After nasotracheal intubation, a 4 cm skin incision is made at the nasolabial fold.

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