Publications by authors named "N Bilge"
Objective/aim: Systemic Lupus Erythematosus (SLE), is common in women of childbearing age and is associated with obstetric complications. The aim of this study was to evaluate the course of pregnancy and its results in SLE patients with a history of pregnancy.
Methods: Pregnant patients with SLE who applied to the Rheumatology outpatient clinic of between 2010 and 2020 were retrospectively screened.
Article Synopsis
- A study evaluates patients with antibodies against myelin oligodendrocyte glycoprotein (anti-MOG-IgG), assessing their clinical, radiological, and demographic characteristics in relation to conditions like optic neuritis and myelitis.
- Among the 104 participants, the majority were women, and the most common diagnoses included NMOSD, isolated optic neuritis, and ADEM, with a notable percentage showing symptoms resembling MS.
- Findings indicate that older patients (>40 years) experienced more severe disability and poorer responses to treatment, highlighting the significance of anti-MOG-IgG in diagnosing NMOSD in patients without anti-NMO antibodies.
Article Synopsis
- The study investigates the effectiveness of two common immunosuppressive agents, methotrexate (MTX) and azathioprine (AZA), as first-line treatments for patients with Takayasu's arteritis (TAK), analyzing patient outcomes and safety.
- A total of 301 TAK patients from 10 centers were included; findings revealed similar remission and relapse rates between MTX and AZA, but a significantly higher rate of vascular surgery in the AZA group compared to MTX.
- The study also noted that patients on MTX were more likely to receive lower doses of glucocorticoids post-treatment compared to those on AZA, indicating different management outcomes between the
Article Synopsis
- A study examined cancer rates in patients with ANCA-associated vasculitis (AAV) by comparing them to cancer risks in the Turkish population and identifying independent risk factors.
- Of the 461 AAV patients tracked, 19 developed cancer after an average follow-up of about 3.4 years, with higher cancer risks noted in older males and those with anti-PR3-ANCA positivity.
- The overall cancer risk for AAV patients was 2.1 times higher than that of the general population, highlighting the need for targeted cancer screening, especially for lung and head-neck cancers in older male patients.